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Published: 2026-06-02
Abstract Views: 23
DOI: https://doi.org/10.52163/yhc.v67iE1.5229
Issue
Vol. 67 No. English Version No 1, 2026
Section
Articles
How to Cite
Thuong, P. T. H., & Hang, N. T. (2026). CLINICAL AND PARACLINICAL CHARACTERISTICS OF FETAL ANEMIA TREATED WITH INTRAUTERINE TRANSFUSION: A CASE SERIES AT HANOI OBSTETRICS AND GYNECOLOGY HOSPITAL. Vietnam Journal of Community Medicine, 67(English Version No 1, 2026). https://doi.org/10.52163/yhc.v67iE1.5229

CLINICAL AND PARACLINICAL CHARACTERISTICS OF FETAL ANEMIA TREATED WITH INTRAUTERINE TRANSFUSION: A CASE SERIES AT HANOI OBSTETRICS AND GYNECOLOGY HOSPITAL

Phan Thi Huyen Thuong1,2, Nguyen Thi Hang2
1 Hanoi Obstetrics and Gynecology Hospital
2 VNU University of Medicine and Pharmacy

Main Article Content

Abstract

Objective: To describe the clinical and paraclinical characteristics of fetal anemia cases treated with intrauterine transfusion at Hanoi Obstetrics and Gynecology Hospital.


Materials and Methods: A prospective case series study was conducted on 05 fetuses diagnosed with anemia (MCA-PSV > 1.5 MoM and/or hydrops fetalis) at the Fetal Intervention Center, Hanoi Obstetrics and Gynecology Hospital, from April 2023 to April 2025, treated with intrauterine blood transfusion.


Results: The mean maternal age was 32.2 ± 2.77 years. The mean gestational age at diagnosis was 28.21 ± 3.02 weeks. The primary etiologies of anemia included complications of monochromatic twin pregnancies (4/5 cases), Parvovirus B19 infection (1/5 cases), and immune-mediated alloimmunization due to atypical antibodies (1/5 cases). Ultrasound findings revealed hydrops fetalis in 60%, cardiomegaly in 80%, and abnormal umbilical cord insertion (velamentous/marginal) in 60%.


Conclusion: Intrauterine transfusion (IUT) is an effective intervention for managing severe fetal anemia. However, late diagnosis remains a significant challenge, emphasizing the need for enhanced screening using MCA-PSV Doppler during the second trimester, particularly in high-risk pregnancies.

Article Details

Keywords

Fetal anemia, intrauterine transfusion, hydrops fetalis.

References

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