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Đã xuất bản: 2026-06-02
Số lượt xem tóm tắt: 16
DOI: https://doi.org/10.52163/yhc.v67iE1.5277
Số xuất bản
Tập 67 Số English Version No 1, 2026
Chuyên mục
Bài báo khoa học
Cách trích dẫn
Thang, N. V., Minh, N. H. H., Ha, N. D., Hang, P. T., & Nam, T. V. (2026). METASTATIC GESTATIONAL TROPHOBLASTIC NEOPLASIA PRESENTING WITH GASTROINTESTINAL HEMORRHAGE AT THE NATIONAL HOSPITAL OF OBSTETRICS AND GYNECOLOGY – A RARE CASE REPORT. Tạp Chí Y học Cộng đồng, 67(English Version No 1, 2026). https://doi.org/10.52163/yhc.v67iE1.5277

METASTATIC GESTATIONAL TROPHOBLASTIC NEOPLASIA PRESENTING WITH GASTROINTESTINAL HEMORRHAGE AT THE NATIONAL HOSPITAL OF OBSTETRICS AND GYNECOLOGY – A RARE CASE REPORT

Nguyen Van Thang1, Nguyen Huu Hoang Minh1, Nguyen Duc Ha1, Phan Thu Hang2, Tran Van Nam3
1 National Hospital of Obstetrics and Gynecology
2 Hanoi Medical University
3 Vietnam University of Traditional Medicine and Pharmacy

Nội dung chính của bài viết

Tóm tắt

Background: Gastrointestinal metastasis of gestational trophoblastic neoplasia (GTN) is a rare complication and poses a direct threat to life.


Case Presentation: A 53-year-old woman presented with persistent gastrointestinal bleeding due to small bowel intussusception. Serum β-hCG was markedly elevated at 392,406 IU/L. Histopathology and immunohistochemistry confirmed metastatic GTN with multi-organ involvement. The patient was treated initially with low-dose EP chemotherapy followed by EMA-CO chemotherapy, achieving good clinical response and rapid decline of β-hCG levels.


Conclusion: Early β-hCG testing and immunohistochemistry are essential for diagnosis of metastatic lesions of unknown origin in women. Initial low-dose chemotherapy may safely control life-threatening complications in high-risk GTN patients.

Chi tiết bài viết

Từ khóa

Gestational trophoblastic neoplasia, gastrointestinal bleeding, choriocarcinoma, β-hCG.

Tài liệu tham khảo

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